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Xenopus importin beta validates human importin beta as a cell cycle negative regulator

BACKGROUND: Human importin beta has been used in all Xenopus laevis in vitro nuclear assembly and spindle assembly studies. This disconnect between species raised the question for us as to whether importin beta was an authentic negative regulator of cell cycle events, or a dominant negative regulato...

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Detalles Bibliográficos
Autores principales: Delmar, Valerie A, Chan, Rene C, Forbes, Douglass J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324082/
https://www.ncbi.nlm.nih.gov/pubmed/18366719
http://dx.doi.org/10.1186/1471-2121-9-14