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Modulation of dopaminergic neurotransmission in rat striatum upon in vitro and in vivo diclofenac treatment1

Diclofenac (DCF) is a widely used non-steroidal anti-inflammatory drug, which also act as a mitochondrial toxin. As it is known that selective mitochondrial complex I inhibition combined with mild oxidative stress causes striatal dopaminergic dysfunction, we tested whether DCF also compromise dopami...

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Detalles Bibliográficos
Autores principales: Milusheva, Elisaveta, Baranyi, Mária, Kittel, Agnes, Fekete, Adam, Zelles, Tibor, Vizi, E Sylvester, Sperlágh, Beáta
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324205/
https://www.ncbi.nlm.nih.gov/pubmed/18036194
http://dx.doi.org/10.1111/j.1471-4159.2007.05141.x

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