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Modulation of dopaminergic neurotransmission in rat striatum upon in vitro and in vivo diclofenac treatment1
Diclofenac (DCF) is a widely used non-steroidal anti-inflammatory drug, which also act as a mitochondrial toxin. As it is known that selective mitochondrial complex I inhibition combined with mild oxidative stress causes striatal dopaminergic dysfunction, we tested whether DCF also compromise dopami...
Autores principales: | Milusheva, Elisaveta, Baranyi, Mária, Kittel, Agnes, Fekete, Adam, Zelles, Tibor, Vizi, E Sylvester, Sperlágh, Beáta |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324205/ https://www.ncbi.nlm.nih.gov/pubmed/18036194 http://dx.doi.org/10.1111/j.1471-4159.2007.05141.x |
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