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Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1

BACKGROUND: Development of therapies for patients with BRCA1 mutations has been hampered by lack of readily available in vitro and in vivo models. We recently showed that transplantation of transgenic mammary tumors as cell suspensions into naïve recipients generates reproducible tumors with remarka...

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Detalles Bibliográficos
Autores principales:	Wright, Mollie H, Robles, Ana I, Herschkowitz, Jason I, Hollingshead, Melinda G, Anver, Miriam R, Perou, Charles M, Varticovski, Lyuba
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329667/ https://www.ncbi.nlm.nih.gov/pubmed/18394172 http://dx.doi.org/10.1186/1476-4598-7-29

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