Regulatory function of the P295-T311 motif of the estrogen receptor α - does proteasomal degradation of the receptor induce emergence of peptides implicated in estrogenic responses?

The way in which estrogen receptor α (ERα) mediates gene transcription and hormone-dependent cancer cell proliferation is now being largely reconsidered in view of several recent discoveries. ERα-mediated transcription appears to be a cyclic and transient process where the proteasome - and thus rece...

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Detalles Bibliográficos
Autores principales: Gallo, Dominique, Haddad, Iman, Laurent, Guy, Vinh, Joëlle, Jacquemotte, Françoise, Jacquot, Yves, Leclercq, Guy
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2008
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329824/
https://www.ncbi.nlm.nih.gov/pubmed/18432312
http://dx.doi.org/10.1621/nrs.06007

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