Differential expression of HOX genes upon activation of leukocyte sub-populations

The HOX genes are key determinants of cellular identity both in early development and in the renewal and differentiation of adult blood cells. Although a number of studies have examined the expression of individual HOX genes in defined blood cell lineages, we have undertaken a comprehensive analysis...

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Detalles Bibliográficos
Autores principales: Morgan, Richard, Whiting, Karen
Formato: Texto
Lenguaje:English
Publicado: Springer Japan 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330060/
https://www.ncbi.nlm.nih.gov/pubmed/18317880
http://dx.doi.org/10.1007/s12185-008-0057-8
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author Morgan, Richard
Whiting, Karen
author_facet Morgan, Richard
Whiting, Karen
author_sort Morgan, Richard
collection PubMed
description The HOX genes are key determinants of cellular identity both in early development and in the renewal and differentiation of adult blood cells. Although a number of studies have examined the expression of individual HOX genes in defined blood cell lineages, we have undertaken a comprehensive analysis of HOX gene expression in resting and activated lymphocytic and monocytic subpopulations. This has revealed distinct patterns of expression between different cell types and resting and activated states. (Main category A: Erythrocytes, Leukocytes and Hematopoiesis, subcategory: 8: Lymphocytes).
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spelling pubmed-23300602008-04-24 Differential expression of HOX genes upon activation of leukocyte sub-populations Morgan, Richard Whiting, Karen Int J Hematol Original Article The HOX genes are key determinants of cellular identity both in early development and in the renewal and differentiation of adult blood cells. Although a number of studies have examined the expression of individual HOX genes in defined blood cell lineages, we have undertaken a comprehensive analysis of HOX gene expression in resting and activated lymphocytic and monocytic subpopulations. This has revealed distinct patterns of expression between different cell types and resting and activated states. (Main category A: Erythrocytes, Leukocytes and Hematopoiesis, subcategory: 8: Lymphocytes). Springer Japan 2008-03-05 2008-04 /pmc/articles/PMC2330060/ /pubmed/18317880 http://dx.doi.org/10.1007/s12185-008-0057-8 Text en © The Japanese Society of Hematology 2008
spellingShingle Original Article
Morgan, Richard
Whiting, Karen
Differential expression of HOX genes upon activation of leukocyte sub-populations
title Differential expression of HOX genes upon activation of leukocyte sub-populations
title_full Differential expression of HOX genes upon activation of leukocyte sub-populations
title_fullStr Differential expression of HOX genes upon activation of leukocyte sub-populations
title_full_unstemmed Differential expression of HOX genes upon activation of leukocyte sub-populations
title_short Differential expression of HOX genes upon activation of leukocyte sub-populations
title_sort differential expression of hox genes upon activation of leukocyte sub-populations
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330060/
https://www.ncbi.nlm.nih.gov/pubmed/18317880
http://dx.doi.org/10.1007/s12185-008-0057-8
work_keys_str_mv AT morganrichard differentialexpressionofhoxgenesuponactivationofleukocytesubpopulations
AT whitingkaren differentialexpressionofhoxgenesuponactivationofleukocytesubpopulations

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