Lentiviral Vpx Accessory Factor Targets VprBP/DCAF1 Substrate Adaptor for Cullin 4 E3 Ubiquitin Ligase to Enable Macrophage Infection

Vpx is a small virion-associated adaptor protein encoded by viruses of the HIV-2/SIVsm lineage of primate lentiviruses that enables these viruses to transduce monocyte-derived cells. This probably reflects the ability of Vpx to overcome an as yet uncharacterized block to an early event in the virus...

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Detalles Bibliográficos
Autores principales: Srivastava, Smita, Swanson, Selene K., Manel, Nicolas, Florens, Laurence, Washburn, Michael P., Skowronski, Jacek
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330158/
https://www.ncbi.nlm.nih.gov/pubmed/18464893
http://dx.doi.org/10.1371/journal.ppat.1000059

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