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Maturation of West Nile Virus Modulates Sensitivity to Antibody-Mediated Neutralization

West Nile virions incorporate 180 envelope (E) proteins that orchestrate the process of virus entry and are the primary target of neutralizing antibodies. The E proteins of newly synthesized West Nile virus (WNV) are organized into trimeric spikes composed of pre-membrane (prM) and E protein heterod...

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Detalles Bibliográficos
Autores principales: Nelson, Steevenson, Jost, Christiane A., Xu, Qinq, Ess, Jessica, Martin, Julie E., Oliphant, Theodore, Whitehead, Stephen S., Durbin, Anna P., Graham, Barney S., Diamond, Michael S., Pierson, Theodore C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330159/
https://www.ncbi.nlm.nih.gov/pubmed/18464894
http://dx.doi.org/10.1371/journal.ppat.1000060

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