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Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation
BACKGROUND: Over a hundred years ago, Wolff originally observed that bone growth and remodeling are exquisitely sensitive to mechanical forces acting on the skeleton. Clinical studies have noted that the size and the strength of bone increase with weight bearing and muscular activity and decrease wi...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335095/ https://www.ncbi.nlm.nih.gov/pubmed/18380899 http://dx.doi.org/10.1186/1471-213X-8-35 |