The underlying mechanisms for development of hypertension in the metabolic syndrome

High blood pressure is an important constituent of the metabolic syndrome. However, the underlying mechanisms for development of hypertension in the metabolic syndrome are very complicated and remain still obscure. Visceral/central obesity, insulin resistance, sympathetic overactivity, oxidative str...

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Detalles Bibliográficos
Autores principales: Yanai, Hidekatsu, Tomono, Yoshiharu, Ito, Kumie, Furutani, Nobuyuki, Yoshida, Hiroshi, Tada, Norio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335113/
https://www.ncbi.nlm.nih.gov/pubmed/18416854
http://dx.doi.org/10.1186/1475-2891-7-10
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author Yanai, Hidekatsu
Tomono, Yoshiharu
Ito, Kumie
Furutani, Nobuyuki
Yoshida, Hiroshi
Tada, Norio
author_facet Yanai, Hidekatsu
Tomono, Yoshiharu
Ito, Kumie
Furutani, Nobuyuki
Yoshida, Hiroshi
Tada, Norio
author_sort Yanai, Hidekatsu
collection PubMed
description High blood pressure is an important constituent of the metabolic syndrome. However, the underlying mechanisms for development of hypertension in the metabolic syndrome are very complicated and remain still obscure. Visceral/central obesity, insulin resistance, sympathetic overactivity, oxidative stress, endothelial dysfunction, activated renin-angiotensin system, increased inflammatory mediators, and obstructive sleep apnea have been suggested to be possible factors to develop hypertension in the metabolic syndrome. Here, we will discuss how these factors influence on development of hypertension in the metabolic syndrome.
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spelling pubmed-23351132008-04-25 The underlying mechanisms for development of hypertension in the metabolic syndrome Yanai, Hidekatsu Tomono, Yoshiharu Ito, Kumie Furutani, Nobuyuki Yoshida, Hiroshi Tada, Norio Nutr J Review High blood pressure is an important constituent of the metabolic syndrome. However, the underlying mechanisms for development of hypertension in the metabolic syndrome are very complicated and remain still obscure. Visceral/central obesity, insulin resistance, sympathetic overactivity, oxidative stress, endothelial dysfunction, activated renin-angiotensin system, increased inflammatory mediators, and obstructive sleep apnea have been suggested to be possible factors to develop hypertension in the metabolic syndrome. Here, we will discuss how these factors influence on development of hypertension in the metabolic syndrome. BioMed Central 2008-04-17 /pmc/articles/PMC2335113/ /pubmed/18416854 http://dx.doi.org/10.1186/1475-2891-7-10 Text en Copyright © 2008 Yanai et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Yanai, Hidekatsu
Tomono, Yoshiharu
Ito, Kumie
Furutani, Nobuyuki
Yoshida, Hiroshi
Tada, Norio
The underlying mechanisms for development of hypertension in the metabolic syndrome
title The underlying mechanisms for development of hypertension in the metabolic syndrome
title_full The underlying mechanisms for development of hypertension in the metabolic syndrome
title_fullStr The underlying mechanisms for development of hypertension in the metabolic syndrome
title_full_unstemmed The underlying mechanisms for development of hypertension in the metabolic syndrome
title_short The underlying mechanisms for development of hypertension in the metabolic syndrome
title_sort underlying mechanisms for development of hypertension in the metabolic syndrome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335113/
https://www.ncbi.nlm.nih.gov/pubmed/18416854
http://dx.doi.org/10.1186/1475-2891-7-10
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