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A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery
BACKGROUND: Several human pathologies, including neoplasia and ischemic cardiovascular diseases, course with an unbalance between oxygen supply and demand (hypoxia). Cells within hypoxic regions respond with the induction of a specific genetic program, under the control of the Hypoxia Inducible Fact...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346465/ https://www.ncbi.nlm.nih.gov/pubmed/18402654 http://dx.doi.org/10.1186/1471-2121-9-18 |