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Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis

Base excision repair (BER) provides relief from many DNA lesions. While BER enzymes have been characterized biochemically, BER functions within cells are much less understood, in part because replication bypass and double-strand break (DSB) repair can also impact resistance to base damage. To invest...

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Detalles Bibliográficos
Autores principales: Ma, Wenjian, Resnick, Michael A., Gordenin, Dmitry A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346603/
https://www.ncbi.nlm.nih.gov/pubmed/18267974
http://dx.doi.org/10.1093/nar/gkm1148

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