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Sperm-derived histones contribute to zygotic chromatin in humans
BACKGROUND: about 15% to 30% of the DNA in human sperm is packed in nucleosomes and transmission of this fraction to the embryo potentially serves as a mechanism to facilitate paternal epigenetic programs during embryonic development. However, hitherto it has not been established whether these nucle...
Autores principales: | van der Heijden, Godfried W, Ramos, Liliana, Baart, Esther B, van den Berg, Ilse M, Derijck, Alwin AHA, van der Vlag, Johan, Martini, Elena, de Boer, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2358879/ https://www.ncbi.nlm.nih.gov/pubmed/18377649 http://dx.doi.org/10.1186/1471-213X-8-34 |
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