Antigen receptor signalling: a distinctive role for the p110δ isoform of PI3K

The activation of antigen receptors triggers two important signalling pathways originating from phosphatidylinositol(4,5)-bisphosphate [PtdIns(4,5)P(2)]. The first is phospholipase Cγ (PLCγ)-mediated hydrolysis of PtdIns(4,5)P(2), resulting in the activation of Ras, protein kinase C and Ca(2+) flux....

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Detalles Bibliográficos
Autores principales: Okkenhaug, Klaus, Ali, Khaled, Vanhaesebroeck, Bart
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2358943/
https://www.ncbi.nlm.nih.gov/pubmed/17208518
http://dx.doi.org/10.1016/j.it.2006.12.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2358943/
https://www.ncbi.nlm.nih.gov/pubmed/17208518
http://dx.doi.org/10.1016/j.it.2006.12.007

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