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Irinotecan+5-fluorouracil with concomitant pre-operative radiotherapy in locally advanced non-resectable rectal cancer: a phase I/II study
In the UK, 10% of patients diagnosed with rectal cancer have inoperable disease at presentation. This study ascertained whether the resectability rate of inoperable locally advanced rectal cancer was improved by administration of intravenous irinotecan, 5-fluorouracil (5-FU) and pelvic radiotherapy....
Autores principales: | Iles, S M, Gollins, S W, Susnerwala, S, Haylock, B, Myint, S, Biswas, A, Swindell, R, Levine, E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359647/ https://www.ncbi.nlm.nih.gov/pubmed/18349840 http://dx.doi.org/10.1038/sj.bjc.6604292 |
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