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The endogenous anti-angiogenic VEGF isoform, VEGF(165)b inhibits human tumour growth in mice
Vascular endothelial growth factor-A is widely regarded as the principal stimulator of angiogenesis required for tumour growth. VEGF is generated as multiple isoforms of two families, the pro-angiogenic family generated by proximal splice site selection in the terminal exon, termed VEGF(xxx), and th...
Autores principales: | Rennel, E S, Waine, E, Guan, H, Schüler, Y, Leenders, W, Woolard, J, Sugiono, M, Gillatt, D, Kleinerman, E S, Bates, D O, Harper, S J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359649/ https://www.ncbi.nlm.nih.gov/pubmed/18349828 http://dx.doi.org/10.1038/sj.bjc.6604309 |
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