Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype

CA IX is a hypoxia-induced, cancer-associated carbonic anhydrase isoform with functional involvement in pH control and cell adhesion. Here we describe an alternative splicing variant of the CA9 mRNA, which does not contain exons 8–9 and is expressed in tumour cells independently of hypoxia. It is al...

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Detalles Bibliográficos
Autores principales: Barathova, M, Takacova, M, Holotnakova, T, Gibadulinova, A, Ohradanova, A, Zatovicova, M, Hulikova, A, Kopacek, J, Parkkila, S, Supuran, C T, Pastorekova, S, Pastorek, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359689/
https://www.ncbi.nlm.nih.gov/pubmed/18026188
http://dx.doi.org/10.1038/sj.bjc.6604111

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