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DNA cleavage and binding selectivity of a heterodinuclear Pt–Cu(3-Clip-Phen) complex

The synthesis and nuclease activity of a new bifunctional heterodinuclear platinum–copper complex are reported. The design of this ditopic coordination compound is based on the specific mode of action of each component, namely, cisplatin and Cu(3-Clip-Phen), where 3-Clip-Phen is 1-(1,10-phenanthroli...

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Detalles Bibliográficos
Autores principales:	de Hoog, Paul, Pitié, Marguerite, Amadei, Giulio, Gamez, Patrick, Meunier, Bernard, Kiss, Robert, Reedijk, Jan
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2008
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359831/ https://www.ncbi.nlm.nih.gov/pubmed/18270754 http://dx.doi.org/10.1007/s00775-008-0346-y

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