Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicin-induced cardiotoxicity

Formaldehyde has been previously shown to play a dominant role in promoting synergy between doxorubicin (Dox) and formaldehyde-releasing butyric acid (BA) prodrugs in killing cancer cells. In this work, we report that these prodrugs also protect neonatal rat cardiomyocytes and adult mice against tox...

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Detalles Bibliográficos
Autores principales: Rephaeli, A, Waks-Yona, S, Nudelman, A, Tarasenko, I, Tarasenko, N, Phillips, D R, Cutts, S M, Kessler-Icekson, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359917/
https://www.ncbi.nlm.nih.gov/pubmed/17473824
http://dx.doi.org/10.1038/sj.bjc.6603781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359917/
https://www.ncbi.nlm.nih.gov/pubmed/17473824
http://dx.doi.org/10.1038/sj.bjc.6603781

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