Cargando…

Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma

Cellular mechanisms that account for tumour osteolysis associated with Ewing's sarcoma are uncertain. Osteoclasts are marrow-derived multinucleated cells (MNCs) that effect tumour osteolysis. Osteoclasts are known to form from macrophages by both receptor activator for nuclear factor-κB (RANK)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lau, Y S, Adamopoulos, I E, Sabokbar, A, Giele, H, Gibbons, C L M H, Athanasou, N A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359921/ https://www.ncbi.nlm.nih.gov/pubmed/17533390 http://dx.doi.org/10.1038/sj.bjc.6603774

Ejemplares similares

Malignant melanoma and bone resorption
por: Lau, Y S, et al.
Publicado: (2006)

Variability in functional p53 reactivation by PRIMA-1(Met)/APR-246 in Ewing sarcoma
por: Aryee, D N T, et al.
Publicado: (2013)

Stable interference of EWS–FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target
por: Herrero-Martín, D, et al.
Publicado: (2009)

Localized Ewing sarcoma of the tibia
por: Kashima, Takeshi G, et al.
Publicado: (2013)

Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1–PI3K–Rac1 pathway
por: Kamura, S, et al.
Publicado: (2010)

Elevated preoperative neutrophil/lymphocyte ratio is associated with poor prognosis in soft-tissue sarcoma patients
por: Szkandera, J, et al.
Publicado: (2013)

Metal wear-induced pseudotumour following an endoprosthetic knee replacement for Ewing sarcoma
por: Craig, Richard, et al.
Publicado: (2017)

Co-detection of members of the urokinase plasminogen activator system in tumour tissue and serum correlates with a poor prognosis for soft-tissue sarcoma patients
por: Taubert, H, et al.
Publicado: (2010)

Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism?
por: Arnould, L, et al.
Publicado: (2006)

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
por: Gray-Schopfer, V C, et al.
Publicado: (2006)

Left renal Ewing's sarcoma: A case study and a review of imaging literature
por: Babapour, Sara, et al.
Publicado: (2020)

Insulin-like growth factor-I receptor activity is essential for Kaposi's sarcoma growth and survival
por: Catrina, S-B, et al.
Publicado: (2005)

Tissue level, activation and cellular localisation of TGF-β1 and association with survival in gastric cancer patients
por: Hawinkels, L J A C, et al.
Publicado: (2007)

Side population cells have the characteristics of cancer stem-like cells/cancer-initiating cells in bone sarcomas
por: Murase, M, et al.
Publicado: (2009)

A prospective study of Kaposi's sarcoma-associated herpesvirus and Epstein–Barr virus in adults with human immunodeficiency virus-1
por: Newton, R, et al.
Publicado: (2006)

Endosialin expression in soft tissue sarcoma as a potential marker of undifferentiated mesenchymal cells
por: Thway, Khin, et al.
Publicado: (2016)

Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells
por: Hirotsu, M, et al.
Publicado: (2009)

New cellular tools reveal complex epithelial–mesenchymal interactions in hepatocarcinogenesis
por: Sagmeister, S, et al.
Publicado: (2008)

A prognostic profile of hypoxia-induced genes for localised high-grade soft tissue sarcoma
por: Aggerholm-Pedersen, Ninna, et al.
Publicado: (2016)

Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies
por: Hampson, L, et al.
Publicado: (2009)

Sox11 expression in astrocytic gliomas: correlation with nestin/c-Met/IDH1-R132H expression phenotypes, p-Stat-3 and survival
por: Korkolopoulou, P, et al.
Publicado: (2013)

Cellular and molecular phenotypes of proliferating stromal cells from human carcinomas
por: Kopantzev, E P, et al.
Publicado: (2010)

Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition
por: Krubasik, D, et al.
Publicado: (2006)

Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation
por: van Miltenburg, M H A M, et al.
Publicado: (2014)

Inflammation and tissue repair markers distinguish the nodular sclerosis and mixed cellularity subtypes of classical Hodgkin's lymphoma
por: Birgersdotter, A, et al.
Publicado: (2009)

Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro
por: Prencipe, M, et al.
Publicado: (2009)

Cellular mechanisms of bone resorption in breast carcinoma
por: Hunt, N C A, et al.
Publicado: (2001)

The relationships between cellular components of the peritumoural inflammatory response, clinicopathological characteristics and survival in patients with primary operable colorectal cancer
por: Richards, C H, et al.
Publicado: (2012)

CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells
por: Maciaczyk, D, et al.
Publicado: (2017)

Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines
por: Prang, N, et al.
Publicado: (2005)

Systematic review and meta-analysis of the impact of tumour budding in colorectal cancer
por: Rogers, A C, et al.
Publicado: (2016)

Cellular changes in boric acid-treated DU-145 prostate cancer cells
por: Barranco, W T, et al.
Publicado: (2006)

The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma
por: Forker, Laura, et al.
Publicado: (2018)

Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer
por: Angst, E, et al.
Publicado: (2006)

Presence of an in situ component is associated with reduced biological aggressiveness of size-matched invasive breast cancer
por: Wong, H, et al.
Publicado: (2010)

Microcalcifications in breast cancer: novel insights into the molecular mechanism and functional consequence of mammary mineralisation
por: Cox, R F, et al.
Publicado: (2012)

Vascular tube formation on matrix metalloproteinase-1-damaged collagen
por: Varani, J, et al.
Publicado: (2008)

Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression
por: Canel, M, et al.
Publicado: (2008)

Different cellular p16(INK4a) localisation may signal different survival outcomes in head and neck cancer
por: Zhao, N, et al.
Publicado: (2012)

Morphological and molecular assessment of apoptotic mechanisms in peripheral neuroblastic tumours
por: Uccini, S, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_pe10okt6s7538jkfi4u052sr57