Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells

To investigate the long-term biological effect of extreme low dose ionising radiation, we irradiated normal human fibroblasts (HFLIII) with carbon ions (290 MeV u(−1), 70 keV μm(−1)) and γ-rays at 1 mGy (total dose) once at a low dose rate (1 mGy 6–8 h(−1)), and observed the cell growth kinetics up...

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Detalles Bibliográficos
Autores principales: Okada, M, Okabe, A, Uchihori, Y, Kitamura, H, Sekine, E, Ebisawa, S, Suzuki, M, Okayasu, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359922/
https://www.ncbi.nlm.nih.gov/pubmed/17486133
http://dx.doi.org/10.1038/sj.bjc.6603775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359922/
https://www.ncbi.nlm.nih.gov/pubmed/17486133
http://dx.doi.org/10.1038/sj.bjc.6603775

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