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Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells
To investigate the long-term biological effect of extreme low dose ionising radiation, we irradiated normal human fibroblasts (HFLIII) with carbon ions (290 MeV u(−1), 70 keV μm(−1)) and γ-rays at 1 mGy (total dose) once at a low dose rate (1 mGy 6–8 h(−1)), and observed the cell growth kinetics up...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359922/ https://www.ncbi.nlm.nih.gov/pubmed/17486133 http://dx.doi.org/10.1038/sj.bjc.6603775 |