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Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells

Grb7 has potential importance in the progression of cancer. We have previously identified a novel peptide that binds to the SH2 domain of Grb7 and inhibits its association with several different receptor tyrosine kinases. We have synthesised the Grb7 peptide, G7-18NATE, with two different cell penet...

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Detalles Bibliográficos
Autores principales:	Pero, S C, Shukla, G S, Cookson, M M, Flemer, S, Krag, D N
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359946/ https://www.ncbi.nlm.nih.gov/pubmed/17426702 http://dx.doi.org/10.1038/sj.bjc.6603732

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