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Characterisation and radioimmunotherapy of L19-SIP, an anti-angiogenic antibody against the extra domain B of fibronectin, in colorectal tumour models

Angiogenesis is a characteristic feature of tumours and other disorders. The human monoclonal antibody L19- SIP targets the extra domain B of fibronectin, a marker of angiogenesis expressed in a range of tumours. The aim of this study was to investigate whole body distribution, tumour localisation a...

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Detalles Bibliográficos
Autores principales:	El-Emir, E, Dearling, J L J, Huhalov, A, Robson, M P, Boxer, G, Neri, D, van Dongen, G A M S, Trachsel, E, Begent, R H J, Pedley, R B
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359968/ https://www.ncbi.nlm.nih.gov/pubmed/17519905 http://dx.doi.org/10.1038/sj.bjc.6603806

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