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Identification of genetic alterations in pancreatic cancer by the combined use of tissue microdissection and array-based comparative genomic hybridisation

Pancreatic ductal adenocarcinoma (PDAC) is characterised pathologically by a marked desmoplastic stromal reaction that significantly reduces the sensitivity and specificity of cytogenetic analysis. To identify genetic alterations that reflect the characteristics of the tumour in vivo, we screened a...

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Detalles Bibliográficos
Autores principales:	Harada, T, Baril, P, Gangeswaran, R, Kelly, G, Chelala, C, Bhakta, V, Caulee, K, Mahon, P C, Lemoine, N R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359995/ https://www.ncbi.nlm.nih.gov/pubmed/17242705 http://dx.doi.org/10.1038/sj.bjc.6603563

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