Study of p53 gene alteration as a biomarker to evaluate the malignant risk of Lugol-unstained lesion with non-dysplasia in the oesophagus

Mutations of the p53 gene are detected frequently in oesophageal dysplasia and cancer. It is unclear whether Lugol-unstained lesions (LULs) with non-dysplastic epithelium (NDE) are precursors of oesophageal squamous cell carcinoma (ESCC). To study the genetic alterations of NDE in the multistep proc...

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Detalles Bibliográficos
Autores principales: Kaneko, K, Katagiri, A, Konishi, K, Kurahashi, T, Ito, H, Kumekawa, Y, Yamamoto, T, Muramoto, T, Kubota, Y, Nozawa, H, Makino, R, Kushima, M, Imawari, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360032/
https://www.ncbi.nlm.nih.gov/pubmed/17285122
http://dx.doi.org/10.1038/sj.bjc.6603582

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