A phase I/II study of irinotecan when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group Study

The objective of this study was to evaluate the maximum tolerated dose (MTD) and recommended dose of irinotecan administered as a 5-day schedule synchronously with 5-fluorouracil (5FU), leucovorin (LV) and preoperative pelvic radiation (45 Gy) for primary borderline/unresectable, locally advanced re...

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Detalles Bibliográficos
Autores principales: Glynne-Jones, R, Falk, S, Maughan, T S, Meadows, H M, Sebag-Montefiore, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360056/
https://www.ncbi.nlm.nih.gov/pubmed/17262086
http://dx.doi.org/10.1038/sj.bjc.6603570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360056/
https://www.ncbi.nlm.nih.gov/pubmed/17262086
http://dx.doi.org/10.1038/sj.bjc.6603570

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