Cellular senescence and chromatin organisation

Despite the potential importance of senescence in tumour suppression, its effector mechanism is poorly understood. Recent studies suggest that alterations in the chromatin environment might add an additional layer of stability to the phenotype. In this review, recent discoveries on the interplay bet...

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Detalles Bibliográficos
Autor principal: Narita, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360064/
https://www.ncbi.nlm.nih.gov/pubmed/17311013
http://dx.doi.org/10.1038/sj.bjc.6603636
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author Narita, M
author_facet Narita, M
author_sort Narita, M
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description Despite the potential importance of senescence in tumour suppression, its effector mechanism is poorly understood. Recent studies suggest that alterations in the chromatin environment might add an additional layer of stability to the phenotype. In this review, recent discoveries on the interplay between senescence and chromatin biology are overviewed.
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spelling pubmed-23600642009-09-10 Cellular senescence and chromatin organisation Narita, M Br J Cancer Review Despite the potential importance of senescence in tumour suppression, its effector mechanism is poorly understood. Recent studies suggest that alterations in the chromatin environment might add an additional layer of stability to the phenotype. In this review, recent discoveries on the interplay between senescence and chromatin biology are overviewed. Nature Publishing Group 2007-03-12 2007-02-20 /pmc/articles/PMC2360064/ /pubmed/17311013 http://dx.doi.org/10.1038/sj.bjc.6603636 Text en Copyright © 2007 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Narita, M
Cellular senescence and chromatin organisation
title Cellular senescence and chromatin organisation
title_full Cellular senescence and chromatin organisation
title_fullStr Cellular senescence and chromatin organisation
title_full_unstemmed Cellular senescence and chromatin organisation
title_short Cellular senescence and chromatin organisation
title_sort cellular senescence and chromatin organisation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360064/
https://www.ncbi.nlm.nih.gov/pubmed/17311013
http://dx.doi.org/10.1038/sj.bjc.6603636
work_keys_str_mv AT naritam cellularsenescenceandchromatinorganisation

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