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Telomere and telomerase in stem cells
Telomeres, guanine-rich tandem DNA repeats of the chromosomal end, provide chromosomal stability, and cellular replication causes their loss. In somatic cells, the activity of telomerase, a reverse transcriptase that can elongate telomeric repeats, is usually diminished after birth so that the telom...
Autores principales: | Hiyama, E, Hiyama, K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360127/ https://www.ncbi.nlm.nih.gov/pubmed/17353922 http://dx.doi.org/10.1038/sj.bjc.6603671 |
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