Cargando…
High-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer
Increased copy numbers of 17q23 chromosomal region have been shown to occur in different tumour types and to be associated with tumour progression and with poor prognosis. Several genes have earlier been proposed as potential oncogenes at this region largely on the grounds of cell lines studies. In...
Autores principales: | Pärssinen, J, Kuukasjärvi, T, Karhu, R, Kallioniemi, A |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360139/ https://www.ncbi.nlm.nih.gov/pubmed/17353917 http://dx.doi.org/10.1038/sj.bjc.6603692 |
Ejemplares similares
-
KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer
por: Birkeland, E, et al.
Publicado: (2012) -
Candidate target genes for loss of heterozygosity on human chromosome 17q21
por: DeMarchis, L, et al.
Publicado: (2004) -
Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses
por: Blancato, J, et al.
Publicado: (2004) -
HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer
por: Benusiglio, P R, et al.
Publicado: (2006) -
Absence of truncating BRIP1 mutations in chromosome 17q-linked hereditary prostate cancer families
por: Ray, A M, et al.
Publicado: (2009)