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Interpretation of microarray data in cancer
Microarray studies aim at identifying homogeneous subtypes of cancer patients, searching for differentially expressed genes in tumours with different characteristics, or predicting the prognosis of patients. Using breast cancer as an example, we discuss the hypotheses underlying these studies, their...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360153/ https://www.ncbi.nlm.nih.gov/pubmed/17342085 http://dx.doi.org/10.1038/sj.bjc.6603673 |
Sumario: | Microarray studies aim at identifying homogeneous subtypes of cancer patients, searching for differentially expressed genes in tumours with different characteristics, or predicting the prognosis of patients. Using breast cancer as an example, we discuss the hypotheses underlying these studies, their power, and the validity and the clinical usefulness of the findings. |
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