Interpretation of microarray data in cancer

Microarray studies aim at identifying homogeneous subtypes of cancer patients, searching for differentially expressed genes in tumours with different characteristics, or predicting the prognosis of patients. Using breast cancer as an example, we discuss the hypotheses underlying these studies, their...

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Detalles Bibliográficos
Autores principales: Michiels, S, Koscielny, S, Hill, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360153/
https://www.ncbi.nlm.nih.gov/pubmed/17342085
http://dx.doi.org/10.1038/sj.bjc.6603673
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author Michiels, S
Koscielny, S
Hill, C
author_facet Michiels, S
Koscielny, S
Hill, C
author_sort Michiels, S
collection PubMed
description Microarray studies aim at identifying homogeneous subtypes of cancer patients, searching for differentially expressed genes in tumours with different characteristics, or predicting the prognosis of patients. Using breast cancer as an example, we discuss the hypotheses underlying these studies, their power, and the validity and the clinical usefulness of the findings.
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spelling pubmed-23601532009-09-10 Interpretation of microarray data in cancer Michiels, S Koscielny, S Hill, C Br J Cancer Minireview Microarray studies aim at identifying homogeneous subtypes of cancer patients, searching for differentially expressed genes in tumours with different characteristics, or predicting the prognosis of patients. Using breast cancer as an example, we discuss the hypotheses underlying these studies, their power, and the validity and the clinical usefulness of the findings. Nature Publishing Group 2007-04-23 2007-03-06 /pmc/articles/PMC2360153/ /pubmed/17342085 http://dx.doi.org/10.1038/sj.bjc.6603673 Text en Copyright © 2007 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Michiels, S
Koscielny, S
Hill, C
Interpretation of microarray data in cancer
title Interpretation of microarray data in cancer
title_full Interpretation of microarray data in cancer
title_fullStr Interpretation of microarray data in cancer
title_full_unstemmed Interpretation of microarray data in cancer
title_short Interpretation of microarray data in cancer
title_sort interpretation of microarray data in cancer
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360153/
https://www.ncbi.nlm.nih.gov/pubmed/17342085
http://dx.doi.org/10.1038/sj.bjc.6603673
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