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New germline mutations in the hypervariable minisatellite CEB1 in the parents of children with leukaemia

Gardner and co-workers advanced the hypothesis that the Seascale leukaemia cluster could have been caused by new mutations in germ cells, induced by paternal preconceptional irradiation (PPI) exposure at the Sellafield nuclear installation. Since evidence has shown that PPI can increase the de novo...

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Detalles Bibliográficos
Autores principales:	Davies, B G, Hussain, A, Ring, S M, Birch, J M, Eden, T O B, Reeves, M, Dubrova, Y E, Taylor, G M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360154/ https://www.ncbi.nlm.nih.gov/pubmed/17387343 http://dx.doi.org/10.1038/sj.bjc.6603706

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