DNA repair capacity as a possible biomarker of breast cancer risk in female BRCA1 mutation carriers

The BRCA1 gene product helps to maintain genomic integrity through its participation in the cellular response to DNA damage: specifically, the repair of double-stranded DNA breaks. An impaired cellular response to DNA damage is a plausible mechanism whereby BRCA1 mutation carriers are at increased r...

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Detalles Bibliográficos
Autores principales: Kotsopoulos, J, Chen, Z, Vallis, K A, Poll, A, Ainsworth, P, Narod, S A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360222/
https://www.ncbi.nlm.nih.gov/pubmed/17213827
http://dx.doi.org/10.1038/sj.bjc.6603528

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