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Profilin-1 is a negative regulator of mammary carcinoma aggressiveness

Expression of profilin-1 (Pfn1) is downregulated in breast cancer cells, the functional significance of which is yet to be understood. To address this question, in this study we evaluated how perturbing Pfn1 affects motility and invasion of breast cancer cells. We show that loss of Pfn1 expression l...

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Detalles Bibliográficos
Autores principales: Zou, L, Jaramillo, M, Whaley, D, Wells, A, Panchapakesa, V, Das, T, Roy, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360229/
https://www.ncbi.nlm.nih.gov/pubmed/17940506
http://dx.doi.org/10.1038/sj.bjc.6604038