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Combinatorial experimental protocols for Erbicin-derived immunoagents and Herceptin

Erbicin is a human anti-ErbB2 single-chain antibody fragment with high affinity and selectivity for ErbB2-positive cancer cells. Two anti-ErbB2 immunoconjugates, called Erb-hRNase and Erb-hcAb, have been prepared and found to be selectively cytotoxic on ErbB2-positive cancer cells in vitro and vivo....

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Detalles Bibliográficos
Autores principales: De Lorenzo, C, Troise, F, Cafaro, V, D'Alessio, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360235/
https://www.ncbi.nlm.nih.gov/pubmed/17923870
http://dx.doi.org/10.1038/sj.bjc.6604022