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Combinatorial experimental protocols for Erbicin-derived immunoagents and Herceptin
Erbicin is a human anti-ErbB2 single-chain antibody fragment with high affinity and selectivity for ErbB2-positive cancer cells. Two anti-ErbB2 immunoconjugates, called Erb-hRNase and Erb-hcAb, have been prepared and found to be selectively cytotoxic on ErbB2-positive cancer cells in vitro and vivo....
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360235/ https://www.ncbi.nlm.nih.gov/pubmed/17923870 http://dx.doi.org/10.1038/sj.bjc.6604022 |