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Capecitabine in combination with docetaxel and mitomycin C in patients with pre-treated tumours: results of an extended phase-I trial
Preclinical data suggest that the anti-tumour activity of capecitabine is enhanced by taxanes and mitomycin C through up-regulation of thymidine phosphorylase (TP). Here, we studied safety and efficacy of the combination of capecitabine with docetaxel and mitomycin C. Two dose levels (DL) were inves...
Autores principales: | Ernst, T, Merx, K, Gnad-Vogt, U, Lukan, N, Kripp, M, Schultheis, B, Hochhaus, A, Hofheinz, R-D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360249/ https://www.ncbi.nlm.nih.gov/pubmed/18000507 http://dx.doi.org/10.1038/sj.bjc.6604067 |
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