Prenatal X-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes

We investigated childhood brain tumours by histological subtype in relation to prenatal X-ray among all children, less than 15 years of age, born in Sweden between 1975 and 1984. For each case, one control was randomly selected from the Medical Birth Register, and exposure data on prenatal X-ray wer...

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Autores principales: Stålberg, K, Haglund, B, Axelsson, O, Cnattingius, S, Pfeifer, S, Kieler, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360258/
https://www.ncbi.nlm.nih.gov/pubmed/17971773
http://dx.doi.org/10.1038/sj.bjc.6604046
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author Stålberg, K
Haglund, B
Axelsson, O
Cnattingius, S
Pfeifer, S
Kieler, H
author_facet Stålberg, K
Haglund, B
Axelsson, O
Cnattingius, S
Pfeifer, S
Kieler, H
author_sort Stålberg, K
collection PubMed
description We investigated childhood brain tumours by histological subtype in relation to prenatal X-ray among all children, less than 15 years of age, born in Sweden between 1975 and 1984. For each case, one control was randomly selected from the Medical Birth Register, and exposure data on prenatal X-ray were extracted blindly from antenatal medical records. Additional information on maternal reproductive history was obtained from the Medical Birth Register. We found no overall increased risk for childhood brain tumour after prenatal abdominal X-ray exposure (adjusted odds ratio (OR): 1.02, 95% confidence interval (CI): 0.64–1.62); primitive neuroectodermal tumours had the highest risk estimate (OR: 1.88, 95% CI: 0.92–3.83).
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spelling pubmed-23602582009-09-10 Prenatal X-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes Stålberg, K Haglund, B Axelsson, O Cnattingius, S Pfeifer, S Kieler, H Br J Cancer Epidemiology We investigated childhood brain tumours by histological subtype in relation to prenatal X-ray among all children, less than 15 years of age, born in Sweden between 1975 and 1984. For each case, one control was randomly selected from the Medical Birth Register, and exposure data on prenatal X-ray were extracted blindly from antenatal medical records. Additional information on maternal reproductive history was obtained from the Medical Birth Register. We found no overall increased risk for childhood brain tumour after prenatal abdominal X-ray exposure (adjusted odds ratio (OR): 1.02, 95% confidence interval (CI): 0.64–1.62); primitive neuroectodermal tumours had the highest risk estimate (OR: 1.88, 95% CI: 0.92–3.83). Nature Publishing Group 2007-12-03 2007-10-30 /pmc/articles/PMC2360258/ /pubmed/17971773 http://dx.doi.org/10.1038/sj.bjc.6604046 Text en Copyright © 2007 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiology
Stålberg, K
Haglund, B
Axelsson, O
Cnattingius, S
Pfeifer, S
Kieler, H
Prenatal X-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes
title Prenatal X-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes
title_full Prenatal X-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes
title_fullStr Prenatal X-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes
title_full_unstemmed Prenatal X-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes
title_short Prenatal X-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes
title_sort prenatal x-ray exposure and childhood brain tumours: a population-based case–control study on tumour subtypes
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360258/
https://www.ncbi.nlm.nih.gov/pubmed/17971773
http://dx.doi.org/10.1038/sj.bjc.6604046
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