Cargando…

Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma

Malignant melanoma is the most lethal of the skin cancers and the UK incidence is rising faster than that of any other cancer. Angiogenesis – the growth of new vessels from preexisting vasculature – is an absolute requirement for tumour survival and progression beyond a few hundred microns in diamet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pritchard-Jones, R O, Dunn, D B A, Qiu, Y, Varey, A H R, Orlando, A, Rigby, H, Harper, S J, Bates, D O
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360298/ https://www.ncbi.nlm.nih.gov/pubmed/17595666 http://dx.doi.org/10.1038/sj.bjc.6603839

Ejemplares similares

VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo
por: Rennel, E S, et al.
Publicado: (2009)

Detection of VEGF-A(xxx)b Isoforms in Human Tissues
por: Bates, David O., et al.
Publicado: (2013)

VEGF(165)b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy
por: Varey, A H R, et al.
Publicado: (2008)

Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer
por: Kut, C, et al.
Publicado: (2007)

VEGF directly suppresses activation of T cells from ascites secondary to ovarian cancer via VEGF receptor type 2
por: Gavalas, N G, et al.
Publicado: (2012)

MDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics
por: Di Benedetto, Melanie, et al.
Publicado: (2015)

Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes
por: Alfaro, C, et al.
Publicado: (2009)

Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma
por: Yoshikawa, D, et al.
Publicado: (2008)

Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression
por: Couvelard, A, et al.
Publicado: (2005)

Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumours
por: Salto-Tellez, M, et al.
Publicado: (2007)

Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway
por: Joshi, H, et al.
Publicado: (2012)

Prognostic and predictive value of VEGF, sVEGFR-2 and CEA in mCRC studies comparing cediranib, bevacizumab and chemotherapy
por: Jürgensmeier, J M, et al.
Publicado: (2013)

Combined analysis of VEGF and EGFR predicts complete tumour response in rectal cancer treated with preoperative radiotherapy
por: Zlobec, I, et al.
Publicado: (2008)

Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer
por: Bando, H, et al.
Publicado: (2005)

Intracrine VEGF signalling mediates colorectal cancer cell migration and invasion
por: Bhattacharya, Rajat, et al.
Publicado: (2017)

VEGF and VEGFR polymorphisms affect clinical outcome in advanced renal cell carcinoma patients receiving first-line sunitinib
por: Scartozzi, M, et al.
Publicado: (2013)

Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer
por: Sasahira, T, et al.
Publicado: (2012)

A peptide corresponding to the neuropilin-1-binding site on VEGF(165) induces apoptosis of neuropilin-1-expressing breast tumour cells
por: Barr, M P, et al.
Publicado: (2005)

The balance of VEGF-C and VEGFR-3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer
por: Takizawa, H, et al.
Publicado: (2006)

Protumoral roles of melanoma inhibitory activity 2 in oral squamous cell carcinoma
por: Kurihara, M, et al.
Publicado: (2013)

Semaphorin, neuropilin and VEGF expression in glial tumours: SEMA3G, a prognostic marker?
por: Karayan-Tapon, L, et al.
Publicado: (2008)

Platelet releasate promotes breast cancer growth and angiogenesis via VEGF–integrin cooperative signalling
por: Jiang, Lei, et al.
Publicado: (2017)

Lymphatic density and metastatic spread in human malignant melanoma
por: Shields, J D, et al.
Publicado: (2004)

The endogenous anti-angiogenic VEGF isoform, VEGF(165)b inhibits human tumour growth in mice
por: Rennel, E S, et al.
Publicado: (2008)

VEGF in the lung: a role for novel isoforms
por: Varet, Julia, et al.
Publicado: (2010)

Absence of VHL gene alteration and high VEGF expression are associated with tumour aggressiveness and poor survival of renal-cell carcinoma
por: Patard, J-J, et al.
Publicado: (2009)

HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
por: Kurosu, T, et al.
Publicado: (2011)

The VEGF pathway and the AKT/mTOR/p70S6K1 signalling pathway in human epithelial ovarian cancer
por: Trinh, X B, et al.
Publicado: (2009)

Malignant melanoma and bone resorption
por: Lau, Y S, et al.
Publicado: (2006)

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level
por: Tanaka, Tsutomu, et al.
Publicado: (2016)

CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration
por: Braig, S, et al.
Publicado: (2011)

Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma
por: Carter, Julia H, et al.
Publicado: (2016)

VEGF‐A(165)b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF‐A splice isoforms from the kidney
por: Stevens, Megan, et al.
Publicado: (2017)

TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion
por: Boecke, A, et al.
Publicado: (2013)

NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity
por: Wang, H, et al.
Publicado: (2012)

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
por: Gray-Schopfer, V C, et al.
Publicado: (2006)

Strong expression of ID1 protein is associated with decreased survival, increased expression of ephrin-A1/EPHA2, and reduced thrombospondin-1 in malignant melanoma
por: Straume, O, et al.
Publicado: (2005)

Isoforms of endothelin-converting enzyme-1 (ECE-1) have opposing effects on prostate cancer cell invasion
por: Lambert, L A, et al.
Publicado: (2008)

Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis
por: Walsh, N, et al.
Publicado: (2010)

TYRP1 mRNA expression in melanoma metastases correlates with clinical outcome
por: Journe, F, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_8fn4h05ihru0ju2de8bfdfedpe