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Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma

Deregulated expression of genes encoding members of the S100 family of calcium-binding proteins has been associated with the malignant progression of multiple tumour types. Using a pharmacological expression reactivation approach, we screened 16 S100 genes for evidence of epigenetic regulation in me...

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Detalles Bibliográficos
Autores principales: Lindsey, J C, Lusher, M E, Anderton, J A, Gilbertson, R J, Ellison, D W, Clifford, S C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360310/
https://www.ncbi.nlm.nih.gov/pubmed/17579622
http://dx.doi.org/10.1038/sj.bjc.6603852