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An α-fetoprotein-derived peptide reduces the uterine hyperplasia and increases the antitumour effect of tamoxifen
Tamoxifen (Tam) is effective for the treatment and prevention of breast cancer. However, it has toxic drawbacks and has limited-duration utility because, over time, human tumours become refractory to Tam. Recently, a new nontoxic peptide, α-fetoprotein-derived peptide (AFPep) has been proposed for t...
Autores principales: | Andersen, T T, Georgekutty, J, DeFreest, L A, Amaratunga, G, Narendran, A, Lemanski, N, Jacobson, H I, Bennett, J A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360332/ https://www.ncbi.nlm.nih.gov/pubmed/17637684 http://dx.doi.org/10.1038/sj.bjc.6603882 |
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