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FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome

This study examines the clinical impact of PTEN genomic deletions using fluorescence in situ hybridisation (FISH) analysis of 107 prostate cancers, with follow-up information covering a period of up to 10 years. Tissue microarray analysis using interphase FISH indicated that hemizygous PTEN losses w...

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Detalles Bibliográficos
Autores principales: Yoshimoto, M, Cunha, I W, Coudry, R A, Fonseca, F P, Torres, C H, Soares, F A, Squire, J A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360375/
https://www.ncbi.nlm.nih.gov/pubmed/17700571
http://dx.doi.org/10.1038/sj.bjc.6603924