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Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo

Expression of the chemokine receptor CXCR4 allows breast cancer cells to migrate towards specific metastatic target sites which constitutively express CXCL12. In this study, we determined whether this interaction could be disrupted using short-chain length heparin oligosaccharides. Radioligand compe...

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Detalles Bibliográficos
Autores principales:	Mellor, P, Harvey, J R, Murphy, K J, Pye, D, O'Boyle, G, Lennard, T W J, Kirby, J A, Ali, S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360379/ https://www.ncbi.nlm.nih.gov/pubmed/17726466 http://dx.doi.org/10.1038/sj.bjc.6603928

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