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Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia

B-cell chronic lymphocytic leukaemia (B-CLL) is characterised by the progressive accumulation of monoclonal CD5(+) B cells. In a previous study, we have analysed the expression profile of apoptosis-regulating genes using a cDNA-based microarray and found overexpression of the antiapoptotic bcl-2 fam...

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Detalles Bibliográficos
Autores principales:	Olsson, A, Norberg, M, ökvist, A, Derkow, K, Choudhury, A, Tobin, G, Celsing, F, österborg, A, Rosenquist, R, Jondal, M, Osorio, L M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360383/ https://www.ncbi.nlm.nih.gov/pubmed/17726463 http://dx.doi.org/10.1038/sj.bjc.6603951

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