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A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials
Recruitment to cancer clinical trials needs to be improved, as does patient knowledge and understanding about clinical trials, in order for patients to make an informed choice about whether or not to take part. Audiovisual patient information (AVPI) has been shown to improve knowledge and understand...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360384/ https://www.ncbi.nlm.nih.gov/pubmed/17848908 http://dx.doi.org/10.1038/sj.bjc.6603943 |
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author | Hutchison, C Cowan, C McMahon, T Paul, J |
author_facet | Hutchison, C Cowan, C McMahon, T Paul, J |
author_sort | Hutchison, C |
collection | PubMed |
description | Recruitment to cancer clinical trials needs to be improved, as does patient knowledge and understanding about clinical trials, in order for patients to make an informed choice about whether or not to take part. Audiovisual patient information (AVPI) has been shown to improve knowledge and understanding in various areas of practice, but there is limited information about its effect in the cancer clinical trial setting, particularly in relation to consent rates. In this study, 173 patients were randomised to receive either the AVPI, in addition to the standard trial-specific written information, or the written information alone. There was no difference in clinical trial recruitment rates between the two groups with similar study entry rates: 72.1% in the AVPI group and 75.9% in the standard information group. The estimated odds ratio for refusal (intervention/no intervention) was 1.19 (95% CI 0.55–2.58, P=0.661). Knowledge scores increased more in the AVPI group compared to the standard group (P=0.0072). The change in anxiety score between the arms was also statistically significant (P=0.011) with anxiety improving in the intervention arm more than in the no intervention arm. Audiovisual patient information was shown to be a useful tool in improving patient knowledge and anxiety, but further work is necessary in relation to its effect on clinical trial recruitment rates. |
format | Text |
id | pubmed-2360384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-23603842009-09-10 A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials Hutchison, C Cowan, C McMahon, T Paul, J Br J Cancer Clinical Study Recruitment to cancer clinical trials needs to be improved, as does patient knowledge and understanding about clinical trials, in order for patients to make an informed choice about whether or not to take part. Audiovisual patient information (AVPI) has been shown to improve knowledge and understanding in various areas of practice, but there is limited information about its effect in the cancer clinical trial setting, particularly in relation to consent rates. In this study, 173 patients were randomised to receive either the AVPI, in addition to the standard trial-specific written information, or the written information alone. There was no difference in clinical trial recruitment rates between the two groups with similar study entry rates: 72.1% in the AVPI group and 75.9% in the standard information group. The estimated odds ratio for refusal (intervention/no intervention) was 1.19 (95% CI 0.55–2.58, P=0.661). Knowledge scores increased more in the AVPI group compared to the standard group (P=0.0072). The change in anxiety score between the arms was also statistically significant (P=0.011) with anxiety improving in the intervention arm more than in the no intervention arm. Audiovisual patient information was shown to be a useful tool in improving patient knowledge and anxiety, but further work is necessary in relation to its effect on clinical trial recruitment rates. Nature Publishing Group 2007-09-11 2007-09-11 /pmc/articles/PMC2360384/ /pubmed/17848908 http://dx.doi.org/10.1038/sj.bjc.6603943 Text en Copyright © 2007 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Clinical Study Hutchison, C Cowan, C McMahon, T Paul, J A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials |
title | A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials |
title_full | A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials |
title_fullStr | A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials |
title_full_unstemmed | A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials |
title_short | A randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials |
title_sort | randomised controlled study of an audiovisual patient information intervention on informed consent and recruitment to cancer clinical trials |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360384/ https://www.ncbi.nlm.nih.gov/pubmed/17848908 http://dx.doi.org/10.1038/sj.bjc.6603943 |
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