Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer

Studies of families who segregate BRCA2 mutations have found that men who carry disease-associated mutations have an increased risk of prostate cancer, particularly early-onset disease. A study of sporadic prostate cancer in the UK reported a prevalence of 2.3% for protein-truncating BRCA2 mutations...

Descripción completa

Detalles Bibliográficos
Autores principales: Agalliu, I, Karlins, E, Kwon, E M, Iwasaki, L M, Diamond, A, Ostrander, E A, Stanford, J L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360390/
https://www.ncbi.nlm.nih.gov/pubmed/17700570
http://dx.doi.org/10.1038/sj.bjc.6603929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360390/
https://www.ncbi.nlm.nih.gov/pubmed/17700570
http://dx.doi.org/10.1038/sj.bjc.6603929

Ejemplares similares