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Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer

The role of secreted frizzled-related protein (SFRP) genes in gastric cancer remains largely unknown. We determined the frequency and functional significance of SFRPs hypermethylation in human gastric cancer. The expression and methylation status of four SFRP members (SFRP1, 2, 4, and 5) in primary...

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Detalles Bibliográficos
Autores principales:	Cheng, Y Y, Yu, J, Wong, Y P, Man, E P S, To, K F, Jin, V X, Li, J, Tao, Q, Sung, J J Y, Chan, F K L, Leung, W K
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360406/ https://www.ncbi.nlm.nih.gov/pubmed/17848950 http://dx.doi.org/10.1038/sj.bjc.6603968

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