Adenovirus DNA is detected at increased frequency in Guthrie cards from children who develop acute lymphoblastic leukaemia

Epidemiological evidence suggests that childhood acute lymphoblastic leukaemia (ALL) may be initiated by an in infection in utero. Adenovirus DNA was detected in 13 of 49 neonatal blood spots from ALL patients but only in 3 of 47 controls (P=0.012) suggesting a correlation between prenatal adenoviru...

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Detalles Bibliográficos
Autores principales: Gustafsson, B, Huang, W, Bogdanovic, G, Gauffin, F, Nordgren, A, Talekar, G, Ornelles, D A, Gooding, L R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360426/
https://www.ncbi.nlm.nih.gov/pubmed/17876329
http://dx.doi.org/10.1038/sj.bjc.6603983
Descripción
Sumario:Epidemiological evidence suggests that childhood acute lymphoblastic leukaemia (ALL) may be initiated by an in infection in utero. Adenovirus DNA was detected in 13 of 49 neonatal blood spots from ALL patients but only in 3 of 47 controls (P=0.012) suggesting a correlation between prenatal adenovirus infection and the development of ALL

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