Cargando…

National study of colorectal cancer genetics

Approximately, a third of all colorectal cancer (CRC) is due to inherited susceptibility. However, high-risk mutations in APC, the mismatch repair (MMR) genes, MUTYH/MYH, SMAD4, ALK3 and STK11/LKB1 are rare and account for <5% of cases. Much of the remaining variation in genetic risk is likely to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Penegar, S, Wood, W, Lubbe, S, Chandler, I, Broderick, P, Papaemmanuil, E, Sellick, G, Gray, R, Peto, J, Houlston, R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Epidemiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360468/ https://www.ncbi.nlm.nih.gov/pubmed/17895893 http://dx.doi.org/10.1038/sj.bjc.6603997

Ejemplares similares

Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk
por: Webb, E, et al.
Publicado: (2008)

CASP8 variants D302H and −652 6N ins/del do not influence the risk of colorectal cancer in the United Kingdom population
por: Pittman, A M, et al.
Publicado: (2008)

Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition
por: Broderick, Peter, et al.
Publicado: (2006)

Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk
por: Bethke, Lara, et al.
Publicado: (2007)

Systematic review of the relationship between family history and lung cancer risk
por: Matakidou, A, et al.
Publicado: (2005)

A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival
por: Morris, Eva J. A., et al.
Publicado: (2015)

A retrospective observational study of the relationship between family history and survival from colorectal cancer
por: Morris, E J A, et al.
Publicado: (2013)

Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer
por: Shiovitz, S, et al.
Publicado: (2014)

Prospective study of dietary patterns and colorectal cancer among Singapore Chinese
por: Butler, L M, et al.
Publicado: (2008)

Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20–44 years: the UK National Case–Control Study of Cervical Cancer
por: Green, J, et al.
Publicado: (2003)

Cigarettes and alcohol in relation to colorectal cancer: the Singapore Chinese Health Study
por: Tsong, W H, et al.
Publicado: (2007)

Estimating the asbestos-related lung cancer burden from mesothelioma mortality
por: McCormack, V, et al.
Publicado: (2012)

Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma
por: Hubner, R A, et al.
Publicado: (2007)

Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer
por: Chubb, Daniel, et al.
Publicado: (2016)

Cholecystectomy and the risk for developing colorectal cancer and distal colorectal adenomas
por: Schernhammer, E S, et al.
Publicado: (2003)

Cholecystectomy and the risk of colorectal cancer in Italy
por: Altieri, A, et al.
Publicado: (2004)

Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study
por: van den Brandt, P A, et al.
Publicado: (2007)

Seasonal variation in the diagnosis of cancer: a study based on national cancer registration in Sweden
por: Lambe, M, et al.
Publicado: (2003)

Alcohol intake and risk of colorectal cancer: Results from the UK Dietary Cohort Consortium
por: Park, J Y, et al.
Publicado: (2010)

Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
por: Ferrucci, L M, et al.
Publicado: (2009)

The impact of aspirin, statins and ACE-inhibitors on the presentation of colorectal neoplasia in a colorectal cancer screening programme
por: Mansouri, D, et al.
Publicado: (2013)

Association between smoking and deaths due to colorectal malignant carcinoma: a national population-based case–control study in China
por: Hou, L, et al.
Publicado: (2014)

Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation Workers
por: Muirhead, C R, et al.
Publicado: (2009)

Do metastatic colorectal cancer patients who present with late relapse after curative surgery have a better survival?
por: Broadbridge, V T, et al.
Publicado: (2013)

A prospective study of serum insulin-like growth factor-I (IGF-I), IGF-II, IGF-binding protein-3 and breast cancer risk
por: Allen, N E, et al.
Publicado: (2005)

Prospective study of the relationship between coffee and tea with colorectal cancer risk: The PLCO Cancer Screening Trial
por: Dominianni, C, et al.
Publicado: (2013)

HPV16 genetic variation and the development of cervical cancer worldwide
por: Cornet, I, et al.
Publicado: (2013)

A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes
por: Antoniou, A C, et al.
Publicado: (2002)

Predictors of adherence to repeat fecal occult blood test in a population-based colorectal cancer screening program
por: Pornet, C, et al.
Publicado: (2014)

Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype
por: Zhu, Y, et al.
Publicado: (2014)

No socioeconomic inequalities in colorectal cancer survival within a randomised clinical trial
por: Nur, U, et al.
Publicado: (2008)

Smoking, alcohol and gastric cancer risk in Korean men: the National Health Insurance Corporation Study
por: Sung, N Y, et al.
Publicado: (2007)

Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes
por: Win, A K, et al.
Publicado: (2011)

Oral contraceptives, reproductive history and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition
por: Tsilidis, K K, et al.
Publicado: (2010)

Severe obesity prior to diagnosis limits survival in colorectal cancer patients evaluated at a large cancer centre
por: Daniel, C R, et al.
Publicado: (2016)

Parity and risk of stomach cancer by sub-site: a national Swedish study
por: Bahmanyar, S, et al.
Publicado: (2008)

Intake of wholegrain products and risk of colorectal cancers in the Diet, Cancer and Health cohort study
por: Egeberg, R, et al.
Publicado: (2010)

Fish consumption and the risk of colorectal cancer: the Ohsaki Cohort Study
por: Sugawara, Y, et al.
Publicado: (2009)

Identifying patients at risk of emergency admission for colorectal cancer
por: Wallace, D, et al.
Publicado: (2014)

Increasing rates of cervical cancer in young women in England: an analysis of national data 1982–2006
por: Foley, G, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_2buqoct3f83l10hfarvs83kl7m