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HIF-1 and tumour radiosensitivity
Hypoxia-inducible factor-1 (HIF-1) plays important roles in regulating radiosensitivity, making it a potentially promising target for tumour radiosensitisation. Here, we discuss the rationale for, and the potential pitfalls of, combining HIF-1 blockade with radiotherapy. In doing so, we describe cli...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360497/ https://www.ncbi.nlm.nih.gov/pubmed/16735998 http://dx.doi.org/10.1038/sj.bjc.6603201 |