MSH6 germline mutations in early-onset colorectal cancer patients without family history of the disease

Germline MLH1 and MSH2 mutations are scarce in young colorectal cancer patients with negative family history of the disease. To evaluate the contribution of germline MSH6 mutations to early-onset colorectal cancer, we have analysed peripheral blood of 38 patients diagnosed with this disease before 4...

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Detalles Bibliográficos
Autores principales: Pinto, C, Veiga, I, Pinheiro, M, Mesquita, B, Jeronimo, C, Sousa, O, Fragoso, M, Santos, L, Moreira-Dias, L, Baptista, M, Lopes, C, Castedo, S, Teixeira, M R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360512/
https://www.ncbi.nlm.nih.gov/pubmed/16940983
http://dx.doi.org/10.1038/sj.bjc.6603318

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